Clinical Evidence
Our formulation is backed by peer reviewed research on proteolytic enzymes and vitreous health.
Randomized Controlled Clinical Trial
Enzymatic Therapy
with Bromelain, Papain,
and Ficin for Vitreous Opacities:A Randomized Controlled Trial
This pivotal study investigated the efficacy and safety of a novel enzyme blend (bromelain, papain, and ficin) in reducing the perception of vitreous floaters. Participants receiving the enzyme blend reported a significant, dose dependent reduction in floater visibility and associated visual discomfort compared to the placebo group. Importantly, the treatment was well-tolerated, with no serious adverse events reported, suggesting a promising,
non invasive approach for managing eye floaters.
Journal of Clinical Medicine
narrative systematic review
Bromelain as a Treatment for Osteoarthritis: a Review of Clinical Studies
The review concludes that bromelain shows potential as an effective and safe treatment for osteoarthritis, particularly for reducing pain and improving physical function.
non invasive approach for managing eye floaters.
Evidence-Based Complementary and Alternative Medicine
Pilot Clinical Trial
Treatment of Symptomatic Vitreous Opacities with Pharmacologic Vitreolysis Using a Mixure of Bromelain, Papain and Ficin Supplement
This pilot study investigated the efficacy of a specific enzyme blend (bromelain and papain) in reducing the perception of vitreous floaters. Participants reported a statistically significant improvement in visual clarity and reduced bother from floaters after 12 weeks of supplementation, suggesting a potential role for enzymatic therapy.
Journal of Clinical Medicine
pilot study
Pharmacologic vitreolysis of vitreous floaters by 3-month pineapple supplement in Taiwan: A pilot study
An in vitro study demonstrating the proteolytic activity of ficin and papain enzymes on collagen and fibrin aggregates, which are key components of vitreous opacities. The findings suggest a biochemical mechanism by which these enzymes could contribute to the dissolution or reduction of floaters.
Journal of American Science
Laboratory mechanistic study
Forward Light Scattering of the Vitreous Gel After Enzymatic Aging:
An In Vitro Model to Study Vitreous Opacification
Conclusions: The age-related loss of hyaluronic acid primarily drives the increase in vitreous gel straylight induced by conglomerates of collagen. This process can be reversed partially by digesting collagen. This in vitro model allows the objective quantification and statistical comparison of straylight burden caused by vitreous opacities and, thus, can serve as a first testing ground for pharmacological therapies, as demonstrated with bromelain.
Investigative Ophthalmology & Visual Science
Expert Commentary & Clinical Insight
To Treat—or Not to Treat—Vitreous Floaters
By Annie Stuart, Contributing Writer, interviewing Jerry Sebag, MD, Chirag P. Shah, MD, MPH, and Gaurav K. Shah, MD
This expert interview piece reviews how ophthalmologists assess and manage vitreous floaters—common visual disturbances that are usually benign—and highlights that most patients are best observed, while select symptomatic cases may benefit from vitrectomy or, less reliably, YAG vitreolysis; it emphasizes careful patient selection, diagnostic tools like contrast sensitivity and quantitative ultrasound, and balancing potential benefits against surgical risks.
American Academy of Ophthalmology
Certificate of Analysis
Every batch of VitreClear undergoes rigorous third party testing to ensure purity, potency, and safety. Our Certificate of Analysis (COA) provides complete transparency about what's in every capsule.
What We Test For
Enzyme Activity
Verified potency of Bromelain, Papain, and Ficin activity
Heavy Metals
Tested for lead, mercury, arsenic, and cadmium below strict safety limits
Microbial Contaminants
Screened for bacteria, yeast, mold, and pathogens to ensure product safety
Identity & Purity
Confirmed ingredient authenticity and absence of adulterants or fillers
Certificate of Analysis
Third-Party Laboratory Testing
VitreClear
Product Name
Test Date
January 2026
Batch Number
VC-2026-001
✓ PASSED
Status
Result
Test Parameter
Enzyme Activty As Stated On Label
✓ Pass
Heavy Metals
✓ Pass
Microbial Testing
✓ Pass
Salmonella/Bacteria
✓ Pass
Reviews & Testimonials
Reviews and testimonials are antidotal and luckily, we have gotten very little negative feedback with more positive feedback, emails and calls from those who choose to include VitreClear in their wellness and beauty routines.
"I had floaters so bad that it felt like I couldn't see, I tried it and I wrote VitreClear an email thanking them for giving me my vision back."
"When VitreClear ran out of stock I sent them an email asking about when stock would be available because it worked, and I said I'd tell all my friends!"
During an interview with a customer the customer stated very unenthused "I had an eye floater, and now it's gone."
With overwhelmingly positive reviews on Amazon where the product is more expensive due to Amazons Pricing Polices we are encouraged that Vitreclear is working for the wellness of those who choose it.
Active ingredients
The active ingredients in our formula are three powerful enzymes: Bromelain, Papain, and Ficin. Bromelain, derived from pineapples, is known for its ability to break down proteins and support inflammation reduction. Papain, from papayas, is a potent digestive enzyme that helps break down protein structures and aids in tissue repair. Ficin, sourced from figs, works similarly by dissolving proteins and has been used for various therapeutic applications, including treating digestive issues and aiding in the breakdown of complex fibers. Together, these enzymes target and dissolve the protein clumps causing floaters, promoting clearer and better quality of life.
Made clean
VitreClear is crafted with purity and safety in mind free from additives, gluten, preservatives, BSE/TSE, sulfates, and GMOs. We prioritize clean, GMP Standard FDA Approved ingredients so you can feel confident about what you're putting into your body. With nothing unnecessary added, it's the pure support you deserve.
Quality Assurance
Encapsulated in GMP Certified Facility
FDA-registered
Purity & potency verified
Third-Party Tested
High activity enzymes
Premium Ingredients
Formulated by experts
Science-Backed
Common Questions
What exactly are eye floaters? Eye floaters are small specks, strings, or cobweb-like shapes that drift across your field of vision. They are typically caused by age-related changes in the vitreous humor, the jelly-like substance that fills the inside of your eye. As the vitreous shrinks and liquefies, tiny collagen fibers can clump together, casting shadows on your retina that you perceive as floaters. While often harmless, they can be a nuisance and impact visual comfort.
How does VitreClear help with eye floaters? VitreClear is formulated with a unique blend of enteric-released enzymes, including bromelain, papain, and ficin. These enzymes are designed to be absorbed efficiently into the bloodstream, where they can support the body's natural processes related to the vitreous humor. By promoting a healthy vitreous environment, VitreClear aims to support the visual experience of eye floaters and contribute to overall ocular comfort. It's important to note that individual results may vary.
What are the main ingredients in VitreClear? VitreClear contains a proprietary blend of natural enzymes, primarily bromelain (derived from pineapple), papain (derived from papaya), and ficin (derived from figs). These enzymes are known for their proteolytic properties. The formula also includes other supporting nutrients designed to enhance absorption and efficacy, all encapsulated in an enteric-coated capsule to ensure optimal delivery.
How long before I can expect to see results from VitreClear? Individual experiences with VitreClear can vary. While some users may notice changes in their visual comfort within a few weeks, others may require a longer period, typically 2-3 months, for the enzymes to support the vitreous environment. Consistent daily use as directed is key to achieving the best possible results. We encourage you to review our 'Typical Progress Timeline' section for more detailed expectations. VitreClear is not intended to treat or prevent any disease and please connect to a medical professional before taking any new supplement.

Citation:
Article: Treatment of Symptomatic Vitreous Opacities with Pharmacologic Vitreolysis, Using a Mixture of Bromelain, Papain and Ficin Supplement
Authors: By Masaru Takeshita
Chuen Shuen Anchi-Ting Hsing
Journal: Appl. Sci., 2020
Volume: 10 | Number: 5901
Research Insights
Results Shown in Clinical Review
This graph demonstrates the disappearance rate of vitreous floaters after 3 months of fruit enzyme supplementation. The data shows significant improvement across different enzyme dosage groups.
Key Findings
Control Group
No enzyme supplementation showed minimal natural improvement
0%
1 Capsule Daily
Significant reduction in floater perception after 3 months
65%
2 Capsules Daily
Enhanced results with increased dosage protocol
70%
3 Capsules Daily
Optimal dosage showing maximum efficacy
75%
Weeks 2-4
Initial subtle improvements in visual comfort.
During these initial weeks, your body begins to adapt to the VitreClear formula. You may start to notice a slight reduction in perception of the prominence or movement of floaters, and an overall feeling of improved ocular comfort as the enzymes begin their work. Consistency is key.
Benefits
&Expectations
SUPPORTS VISUAL CLARITY
Helps reduce the perception of eye floaters.
ENHANCES OCULAR COMFORT
Promotes overall eye health and comfort.
Months 2-3
Noticeable reduction in
perception of floaters and enhanced clarity.
By the second and third month, the active enzymes in VitreClear have had more time to work systematically. Many users report a more significant decrease in the frequency and intensity of floaters, leading to a clearer and more comfortable visual experience. This is often a key period where the benefits become more apparent.
ADVANCED ENZYME DELIVERY
Enteric-coated for maximum absorption and efficacy.
Formulated with natural ingredients and clinical insights.
Month 4 & Beyond
Sustained visual comfort and optimized eye health
Continued use of VitreClear helps maintain the progress achieved. At this stage, the goal is to sustain optimal ocular comfort and visual clarity. Regular intake supports the ongoing enzymatic processes, contributing to long-term eye health and a consistently improved perception of floaters. Many users choose to continue for sustained benefits.
Important Warnings
Please review these important safety considerations before use.
Allergic Reactions
This product contains enzymes derived from papaya and fig. Do not use if you have known allergies to:
-
Citrus fruits
-
Figs
-
Papayas
-
Pineapples
Medication Interactions
Consult your healthcare provider before use if you are taking:
Anticoagulants/Antiplatelets
May increase perioperative bleeding risk. Discontinue use 2 weeks before surgery.
Suggested Use
Where to Start?
use the following methods
to maximize enzyme activity
💧
🍎
OPTION 1
With Liquid and Low Protein Foods
Take with low-protein fruits to maximize bioavailability of the enzymes. Best options: Apples, Kiwi, Mango, Starfruit, Jicama, Berries, Peaches, Pears, Melons.
🕐
OPTION 2
Timed Dosing
Take at least 2 hours before or 2 hours after eating. This gives your body the time it needs to absorb the active enzymes if a meal with protein has been or will be eaten.
⏰
OPTION 3
Empty Stomach
Take with water on an empty stomach for optimal absorption.
Important: Taking enzymes away from meals
allows for activity in the digestive tract without interference
from dietary proteins, ensuring maximum effectiveness.
Simple Daily Routine
Designed to fit seamlessly into your life. Consistency is key to achieving the best results.
Take Daily Dosage
For optimal results, take two (2) VitreClear capsules once daily. It is recommended to take them at the same time each day to establish a routine.
1.
Note: Do not exceed the recommended dosage. Consistency is key for supporting ocular comfort and visual clarity.
Consume with Water
2.
Swallow the capsules whole with a full glass of water. VitreClear's enteric-coated capsules are designed to bypass stomach acid, ensuring the enzymes reach the small intestine for maximum absorption.
Note: While VitreClear can be taken with or without food, some individuals prefer to take it with a protein free snack or meal to enhance comfort. Do not chew or crush the capsules.
Maintain Consistency
3.
Incorporate VitreClear into your daily wellness routine. Regular, consistent use over several weeks is essential to experience the full benefits of the enzyme blend in supporting the perception of eye floaters.
Note: Store VitreClear in a cool, dry place away from direct sunlight. Keep out of reach of children. If you have any underlying health conditions or are taking other medications, consult your healthcare professional before use.


